senescence long covid

Cellular senescence, skin ageing and cellulite

Cellular senescence, skin ageing and cellulite

Cellular senescence, literally meaning “cell aging”, is the process by which cells stop dividing and enter a senile stage characterised by dysfunction and the spreading of inflammation. Cellular senescence leads to the production of pro-inflammatory mediators that can spread inflammation to thousands of other cells in the vicinity of a group of senescent cells or even throughout the body. Cells normally enter cellular senescence after approximately 50 cell divisions (mitoses) and this normal process is known as "replicative senescence". When a cell enters senescence it is selected to be cleared by the immune system, in a process called senolysis…