MMP9

How EGCG in green tea helps protect collagen IV in skin and blood vessels

How EGCG in green tea helps protect collagen IV in skin and blood vessels

This in-vitro study has shown that the main active molecule in green tea, epigallocatechin gallate (EGCG), inhibits the metalloproteinase MMP9 and its precursor proMMP9. MMPs are useful for various body processes, as they are collagen remodelling agents, but excessive MMP synthesis can lead to excessive connective tissue breakdown. Usually MMPs are over-activated by inflammation or free radical damage, i.e. when tissue injury occurs…