natural actives

Forskolin: the most important lipolytic active ingredient

Forskolin: the most important lipolytic active ingredient

Forskolin, is the extract of the South Asian plant coleus forskohlii / plectranthus barbatus. It has been extensively researched for decades for its lipolytic action and is routinely used in lab experiments when it is needed to stimulate lipolysis in fat cells. (Lipolysis refers to fat release from fat cells, leading to fat cell size reduction and, if sustained, eventual fat cell death.) However, due to its high cost (10x more than the highest quality caffeine) it is rarely used in anti-cellulite creams - although it is way more important than caffeine in this regard…

Forskolin, lipolysis and cellulite creams

Forskolin, lipolysis and cellulite creams

The natural lipolytic chemical forskolin was found in this study to release fat from fat cells, via significant cAMP production in fat cells. This study confirms that forskolin is clearly THE strongest natural lipolytic natural active and it is an ideal anti-cellulite…

Gotu kola / centella asiatica: how it works for cellulite and other skin conditions

Gotu kola / centella asiatica: how it works for cellulite and other skin conditions

Centella asiatica (gotu kola) is one of the most important herbs for skincare and skin diseases, due to its multifunctional action. This review summarises the main modes of action of gotu kola on multiple aesthetic and medical skin conditions: acne, acne scars, burns, atopic dermatitis, vitiligo, fibrosis, hair loss and cellulite…

Pterostilbene, resveratrol and hyperpigmentation

Pterostilbene, resveratrol and hyperpigmentation

Pterostilbene is a chemical found in plants that has strong antioxidant and anti-inflammatory properties. These properties make it potentially useful for preventing skin cancer and other skin conditions. However, until recently, there had not been any research examining the effects of pterostilbene on pigment production in the skin…

Apigenin from parsley, chamomile and celery may help prevent cellulite

Apigenin from parsley, chamomile and celery may help prevent cellulite

A new study, published a few days ago (December 2023) looked at the potential antioxidant, anti-aging and anti-cellulite potential of a family of aromatic plants called Apiaceae or Umbelliferae. Common apiaceae plants include ajwain, angelica, anise, asafoetida, caraway, carrot, celery, chervil, coriander, cumin, dill, fennel, lovage, cow parsley, parsley, parsnip and sea holly…

Escin may reduce water retention and cellulite due to an anti-inflammatory effect

Escin may reduce water retention and cellulite due to an anti-inflammatory effect

Escin may reduce inflammation and oedema by acting as a steroid - without the side effects of steroids. This paper states “the anti-inflammatory effects of escin were related to down-regulation of pro-inflammatory mediators (ie, PGE2, TNF-α, and IL-1β), through the increased expression of the glucocorticoid receptor”. In plain English this means that the horse chestnut extract escin (and most probably its chemical cousin esculin, which has similar activity) acts on the same receptor that corticosteroids act.

Red vine leaf extract improves chronic venous insufficiency [Research]

Red vine leaf extract improves chronic venous insufficiency [Research]

Chronic venous insufficiency (CVI) is common in women, especially older or overweight women. Common symptoms include fat accumulation under/inside the skin, oedema (water retention), heavy legs, muscle cramps, pain and varicose veins. Several natural supplements are used for CVI which can help relieve symptoms of the condition, including centella asiatica/gotu kola extract, hesperidin, diosmin, butcher’s broom extract and escin/horse chestnut extract and red vine leaf extract among others.

Hyaluronic acid: water retention, anti-aging, cellulite and weight gain

Hyaluronic acid: water retention, anti-aging, cellulite and weight gain

Everyone is talking about hyaluronic acid. I have been researching and formulating skin products with hyaluronic acid (HA) since 2003 and I have seen HA starting to gain wider popularity from 2010 onwards. In the last five years hyaluronic acid has become the most well-known cosmetic active ingredient. But what is hyaluronic acid, what does it do, how does it work and what is really the best type of hyaluronic acid?

Citrus bioflavonoids skin benefits: cellulite, skin firming, anti-ageing and more

Citrus bioflavonoids skin benefits: cellulite, skin firming, anti-ageing and more

Most women, and an increasing number of men, use anti-ageing skin products to stay young and fight the signs of ageing. In addition, an increasing number of consumers also use nutri-cosmetics, i.e. nutritional supplements that are specifically geared to protecting skin from within. In this article we examine a class of natural compounds that can boost skin health and beauty from both within and outside.